PHENOLIC COMPOUNDS DETERMINATION AND ANTIOXIDANT ACTIVITY OF TEUCRIUM CAVERNARUM

Authors : Fatih GÖĞER, Ayla KAYA, Muhittin DİNÇ, Süleyman Doğu DOĞU

Pages : 229-237

Doi:10.18036/estubtdc.599094

View : 27 | Download : 8

Publication Date : 2019-07-31

Article Type : Research Paper

Abstract :Normal 0 21 false false false TR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normal Tablo"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0cm; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-fareast-language:EN-US;} ABSTRACT The current study was aimed to determine phenolic compounds profile and antioxidant activity of 70% MeOH extract of Teucrium cavernarum   P.H. Davis which is an endemic plant of Turkey.   According to LC-MS/MS analysis of the extract, forsythoside A, forsythoside B, luteolin-7-gucoside, cirsimaritin and cirsiliol were determined as the major compounds. The total phenolic and radical scavenging activities of the extract were also determined. According to antioxidant activity results, IC 50 value of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect was determined as 0.12 ±0.01 mg/mL. 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity was also determined as 1.2 mM trolox equivalent (TEAC).
Keywords : Teucrium cavernarum, Antioxidant activity, LC MS MS, Phenolic