Molecularly Targeted Therapies In Breast Cancer: A Traditional Review

Authors : Büşra İrem Şimşek, Hamza Halıcı, Elif Çadırcı

Pages : 435-448

Doi:10.55262/fabadeczacilik.1444169

View : 50 | Download : 33

Publication Date : 2024-08-25

Article Type : Review Paper

Abstract :Globally, breast cancer stands as the most frequently diagnosed cancer among women, with its incidence continually on the rise. Conventional treatment methods of breast cancer have inherent limitations. Consequently, the development of innovative treatment approaches is imperative. Among these, targeted therapy strategies have emerged as a key point in contemporary clinical research, greatly diversifying the treatment landscape for breast cancer in recent years. The goals of these new treatment strategies are evolving towards a future that can overcome the limitations of traditional treatment methods, protect patients from side effects, and improve patients\' survival rates and life quality. Nowadays, therapeutic agents that bind to preferred targets are used based specifically on various subtypes of breast cancer. The FDA-approved targeted therapeutic agents—such as monoclonal antibodies, gene therapies, immunotherapeutic cancer vaccines, and small molecule inhibitors are reviewed in this article.
Keywords : Moleküler hedefli tedavi, Meme kanseri, Küçük molekül inhibörleri, Monoklonal antikorlar, İmmuterapötik kanser aşıları, Gen terapisi