The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients

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Ahi Evran Tıp Dergisi
Volume:8 Issue:3
The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients

The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients

Authors : Muhammet Salih Ateş, Fikret Keleş, Alp Yıldırım, Zafer Kök, Mustafa Çelik, Bilal İlanbey, Muhammed Fatih Kaleli

Pages : 342-347

Doi:10.46332/aemj.1452480

View : 43 | Download : 18

Publication Date : 2024-12-17

Article Type : Research Paper

Abstract :Purpose: The purpose of this study is to investigate the impact of smoking on platelet indices among patients with acute myocardial infarction (AMI), and to highlight comparative dimensions between smokers and non-smokers. Materials and Methods: A patient diagnosed with AMI and scheduled for coronary angiography between November 2023 and March 2024 was included in this study. Participants were divided into two groups based on their smoking status. Platelet indices, including platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), were compared. Subsequently, the smoking patients were categorized into five groups based on their smoking duration. Results: In the study, which included 224 patients, MPV values in the NSTEMI group among non-smokers were found to be significantly higher compared to the STEMI group (p=0.013). When the relationship between smoking duration and platelet indices was analyzed, it was observed that with increasing smoking duration, platelet indices significantly decreased (p<0.001), platelet count increased (p<0.001), PDW decreased (p=0.02), PCT increased (p=0.001), and MPV decreased (p=0.002). Conclusion: The findings indicate that smoking has significant effects on platelet indices in AMI patients. Particularly, changes in platelet functions associated with increased duration of smoking are of importance for the progression of cardiovascular diseases and the increase in thrombogenic risk. These results highlights the need for a deeper understanding of the effects of smoking on platelet function and the consideration of these effects in the management of cardiovascular risk.
Keywords : akut koroner sendrom, kardiyovasküler risk, trombosit fonksiyonu, tütün

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