Different Approach on our Cells and the Use of CRISPR/Cas 9 Technology: Super Gene'ethic

Authors : Hale Köksoy, Mohammed Saleh Ameen Al Qadri, Serap Karakaya, Pelin Bacak, Elif Senanur Yüksel, Şengül Koçer, Emine Kav, Sümeyra Demir, Ece Demirel, Himmet Akkaya, Ayşe Nur Akmeşe, Ayşenur Taşkaya

Pages : 594-598

Doi:10.54005/geneltip.1332161

View : 129 | Download : 157

Publication Date : 2023-10-25

Article Type : Research Paper

Abstract :Aims: CRISPR/Cas9, a revolutionary genome editing tool derived from a bacterial system, has transformed molecular biology research, enabling precise and versatile modifications to the genome. This study surveyed 300 participants, including instructors, second-year medical students, and patient relatives from Selcuk University Faculty of Medicine, to assess their knowledge, attitudes, and ethical perspectives on gene editing. Methods: A comprehensive survey was conducted, and the participants\' demographics were correlated with their responses. Statistical analysis was performed using SPSS 22.0. Results: The survey revealed significant differences (p<0.05) in attitudes based on gender, age, and participation groups. The age group of 18-29 exhibited the highest participation rate (57.3%), while the age group of 60-65 had the lowest (1%). Approximately 50.3% of participants reported no prior knowledge of CRISPR/Cas9, and 64.3% were university graduates. Obtaining approval from ethics committees was considered crucial by 151 respondents for commencing CRISPR/Cas9 research. Interestingly, 63.3% showed eagerness for genetically modified plants and animals, while only 9% expressed interest in studies related to eternal youth. Additionally, 88% found gene editing studies conflicting with their beliefs. Conclusions: CRISPR/Cas9 holds great promise for biomedicine and healthcare but necessitates enhanced public awareness and informed decision-making. The study highlights the importance of promoting informed discussions on the ethical implications of CRISPR/Cas9 to address the concerns and perceptions of various demographics. These valuable insights contribute to the ongoing discourse on the impact of CRISPR/Cas9 on society.
Keywords : CRISPR Cas9, Genetik manipülasyon, Etik, Genom Düzenleme, Tıbbi Uygulamalar