The Relationship Between Rheumatoid Factor Seropositivity and Impulsivity in Rheumatoid Arthritis and the Potential Clinical Effects of Impulsivity

Authors : Çağrı Öğüt, Alper Yıldırım

Pages : 719-726

View : 136 | Download : 131

Publication Date : 2024-10-31

Article Type : Research Paper

Abstract :Background: Impulsivity is the propensity to make judgments and take action without sufficient planning or foreseeing consequences. Impulsivity is one of the main symptoms of several mental disorders. Studies supporting the association between inflammation and impulsivity are increasing in number. This study aimed to assess the association between impulsivity and rheumatoid factor (RF) in rheumatoid arthritis. Methods: Thirty rheumatoid arthritis patients with RF+ and 22 rheumatoid arthritis patients with RF- were enrolled in this study. Impulsivity was measured using the Barratt Impulsivity Scale (BIS). In addition, Beck Depression Inventory, Beck Anxiety Inventory, Morisky Medication Adherence Scale, Intuitive Eating Scale-2, Health Assessment Questionnaire, and Disease Activity Score-28 were used to evaluate the individuals\' clinical features. Results: In this study, patients with RF+ had higher BIS impulsivity scores than those with RF-. In addition, smoking rates, which may be associated with impulsive behavior, were higher in the RF+ group than in the RF group. Regarding the Morisky Medication Adherence Scale, Beck Anxiety Inventory, Beck Depression Inventory, and Intuitive Eating Scale-2, there was no significant difference between the groups. However, higher scores on impulsivity were positively correlated with higher lymphocyte counts. Conclusions: These results indicate that RF seropositivity in rheumatoid arthritis is associated with impulsivity. The high impulsivity detected in RF+ patients may be the reason why risky behaviors such as smoking are seen more frequently in this group.
Keywords : romatoid artrit, romatoid faktör, inflamasyon, dürtüsellik

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