Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

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Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi
Issue:1
Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

Authors : Tuba MERT, Tuğçe FAFAL, Bijen KIVÇAK, H Tansel ÖZTÜRK

Pages : 17-24

View : 28 | Download : 17

Publication Date : 2010-01-01

Article Type : Research Paper

Abstract :Bu çalışmada, Alcea rosea L.’nin çiceklerinin n-hegzan, metanol, etanol, etil asetat ve su ekstrelerinin, antimikrobiyal ve sitotoksik aktiviteleri değerlendirildi. Ekstrelerin antimikrobiyal aktiviteleri, bakteri olarak Escherichia coli ATCC 29998, Escherichia coli ATCC 25922, ATCC 29213, Staphylococcus epidermidis ATCC 12228, Salmonella thyphimurium CCM 5445, Enterobacter cloacae ATCC 13047, Enterococcus faecalis ATCC 29212, Pseudomonas aeroginosa ATCC 27853 ve mantar olarak Candida albicans ATCC 10239 ’ a karşı disk difüzyon metodu ile tayin edildi. Ekstrelerin sitotoksik aktiviteleri Brine shrimp yöntemiyle değerlendirildi. Etil asetat ekstresi Brine shrimp’e karşı sitotoksik aktivite gösterdi.
Keywords : Alcea rosea L, Malvaceae, sitotoksik aktivite, antimikrobiyal aktivite

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