Histological Typing and Morphological Characterization of Canine Seminomas

Authors : Gözde Yücel Tenekeci, Arda Selin Tunç

Pages : 180-189

Doi:10.31196/huvfd.1361082

View : 77 | Download : 173

Publication Date : 2023-12-22

Article Type : Research Paper

Abstract :The aim of this study was to evaluate seminomas based on cell morphology and histological structures and classify them into subtypes. Thirty canine seminomas were stained with hematoxylin-eosin (HE) and Periodic Acid Schiff (PAS). PAS-positive cases were classified as Classical seminoma (CS) (n:5), while PAS-negative cases were categorized as Spermatocytic seminoma (SS) (n:23). Cases exhibiting both positive and negative staining were evaluated as Spermatocytic/Classical seminoma (n:2). Carcinoma in situ were observed in the cases with Classical seminoma (n:3). The cell morphology and mitotic indices of each case were given in detail. Canine seminomas were classified into three subtypes: intratubular (n:12), diffuse (n:1), and intratubular/diffuse (n:10). As a result, it was thought that SS and CS types could be observed together, and it was observed that the intratubular/diffuse subtype is a third type characterized by its transformation from intratubular to diffuse form.
Keywords : Köpek seminomları, histopatoloji, klasik seminom, spermatositik seminom