Comparative anatomy of the pelvic cavity of rat strains in a translational aspect

Authors : Yasemin Üstündağ, Osman Yılmaz

Pages : 31-38

Doi:10.31196/huvfd.1621777

View : 15 | Download : 0

Publication Date : 2025-06-19

Article Type : Research Paper

Abstract :The anatomy of the pelvic cavity has significant importance in daily clinical applications and surgical interventions such as determining dystocia, surgery of rectal cancers and mesorectal excision, treatment of twisted pouch syndrome and percutaneous sacroiliac screw fixation, and pelvic floor disorders. This study aims to determine the diameters and area calculations of the pelvic cavity in mostly preferred rat strains (Wistar Albino, Brown Norway, Sprague Dawley, and Lewis) and investigate the suitability of rats in translational studies in which anatomical conditions are not a cause of dystocia. In this study, pelvis bones were used. Each group consisted of six rats. They were examined morphologically and morphometrically. According to the Kruskal-Wallis analysis to determine whether there is any difference between strains, significant differences were observed between the strains for the length of the symphysis, oblique diameter, true conjugate, anatomical conjugate, and diagonal conjugate parameters (p<0.05). In conclusion, anatomically, Lewis is the most suitable laboratory rat strain that does not predispose to labor dystocia, followed by the Wistar Albino strain. These two strains may be a choice for studies on physiological dystocia. On the other hand, Sprague Dawley is less suitable for experimental studies involving the pelvic inlet, particularly those related to labor dystocia caused by anatomical factors.
Keywords : Çap, güç doğum, pelvik boşluk, sıçan, translasyonel anatomi

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