Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound

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Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Volume:10 Issue:3
Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound

Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound

Pages : 1857-1864

View : 58 | Download : 12

Publication Date : 2020-09-01

Article Type : Research Paper

Abstract :In this paper, we investigated the antioxidant potential of Quebecol in vitro using several assays. These; Cu2+-Cu+ reducing, DPPH• scavenging, Fe3+-Fe2+reducing, ABTS•+ scavenging. The IC50 amounts of the Quebecol in the DPPH• and ABTS•+ methods were 14.78 and 5.38 μg m1, respectively. Tyrosinase enzyme is a functional oxidase that is extensively divided in nature. It is the main enzyme in melanin synthesis and also is involved in designating the color of mammalian hair and skin. Recently, there has been a remarkable concern to study the inhibitory activity of the tyrosinase enzyme and some inhibitory molecules isolated from natural sources. For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.
Keywords : Quebecol, antioxidant activity, tyrosinase, enzyme inhibition

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