Investigation of Some Biological Activities of Ajuga chamaepitys subsp. chia

Authors : Atiye Nur SAVAŞ, Nurcihan HACIOĞLU, Neslihan DEMİR

Pages : 162-169

Doi:10.21597/jist.1202158

View : 34 | Download : 9

Publication Date : 2023-03-01

Article Type : Research Paper

Abstract :Ajuga L., which is an Eastern Mediterranean element, is popularly known as ground pine, dwarf grass, ground cypress, bitter gourd, wormwood, yeast grass insert ignore into journalissuearticles values(mayasılotu in Turkish); insert ignore into journalissuearticles values(Zeybek and Zeybek, 1994);. Ajuga chamaepitys L. Schreb species has been used since the Middle Ages as a diuretic, antidote for poisonous animal stings, and as an invigorating, wound-healing and diaphoretic plant. This study evaluated antibiofilm, time-kill potential and antioxidant activity of four extracts of A. chamaepitys subsp. chia insert ignore into journalissuearticles values(Schreb.); Arcang. Crystal violet binding assay were used to determinate antibiofilm activities of extracts against test microorganisms insert ignore into journalissuearticles values(4 Gram negative, 3 Gram positive and 1yeast);. Antioxidant activity was evaluated by using 2,2-diphenyl1-picrylhydrazyl and reducing antioxidant capacity methods. The highest antibiofilm activity was obtained in acetone extract against P. aeruginosa ATCC 27853 and S. aureus ATCC 6538P bacteria. In the time-dependent killing test of plant extracts, microbicidal effect was obtained after 24 hours. The highest antioxidant activity was obtained from plants ethyl acetate extract.
Keywords : Ajuga chamaepitys subsp chia, antibiofilm, time kill assay, antioxidant

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