Thyroid function tests after sleeve gastrectomy in euthyroid obese patients

Authors : Oktay Bulur, Doğan Öztürk

Pages : 159-165

Doi:10.17941/agd.1842010

View : 8 | Download : 25

Publication Date : 2026-02-20

Article Type : Research Paper

Abstract :Background and Aims: Obesity is a well-known clinical problem. It has secondary outcomes and complications that cause mortality and morbidity. The aim of this study is to define the alterations in thyroid function tests after sleeve gastrectomy. Materials and Methods: A total of 85 patients, 79 females and 6 males, were included in the study. Each patient’s body mass indexes, free triiodothyronine (freeT3), free thyroxine (freeT4), and thyroid stimulating hormone levels at preoperative and post-operative 6th and 12th month visits were recorded. Thyroid function tests of the patients grouped as group 0: preoperative, group 1: postoperative 6 months, group 2: postoperative 12-month for each test, respectively. All analyses were performed by means of the chemiluminescence method (Liaison®; DiaSorin S.p.A., Saluggia, Italy). Results: Serum freeT3 levels were decreased in all postoperative visits compared to the preoperative period. Median (25% - 75%) values for each visit were as follows: freeT30: 3.04 pg/mL (3.25 - 2.77), freeT31: 2.68 pg/mL (2.9 - 2.36), freeT32: 2.6 pg/mL (2.91 - 2.38). Serum freeT4 levels increased at the post-operative 6th month visit, and then decreased at the post-operative 6th month visit. Median (25% - 75%) values at each visit for were as follows, freeT40: 1.04 ng/dL (1.15 - 0.99), freeT41: 1.06 ng/dL (1.15 - 0.99), freeT42: 1.03 ng/dL (1.3 - 0.94). Serum thyroid stimulating hormone levels were decreased at post operative all visits compared to preoperative period. Median (25% - 75%) values at each visit were as follows: thyroid stimulating hormone0: 2.16 µIU/L (2.81 - 1.49), thyroid stimulating hormone1: 1.48 µIU/L (2.46 - : 0.93), thyroid stimulating hormone2: 1.47 µIU/L (2.3 - 0.92). There was no correlation between the decrease in thyroid stimulating hormone levels and the body mass index decrement after sleeve gastrectomy. Conclusions: We determined a significant decrease in thyroid stimulating hormone and freeT3 levels, and there was a fluctuating pattern in freeT4 levels after sleeve gastrectomy.
Keywords : Obezite, sleeve gastrektomi, tiroid fonksiyon testleri

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