The Role of Systemic Inflammatory Response Markers in Differential Diagnosis of Ovarian Tumors

Authors : Sevgi SERDAR, Günsu KİMYON CÖMERT, Özgün CEYLAN, İrem KAR, Hakan Raşit YALÇIN, Taner TURAN

Pages : 1769-1772

Doi:10.38136/jgon.1278471

View : 24 | Download : 92

Publication Date : 2023-07-03

Article Type : Research Paper

Abstract :Aim: The aim of this study is evaluating the predictive value of preoperative inflammatory blood parameters for differential of serous cystadenoma, serous borderline ovarian tumor insert ignore into journalissuearticles values(BOT); and high-grade serous ovarian insert ignore into journalissuearticles values(HGSOC); carcinoma. Materials and Method: In this single-center study, we retrospectively enrolled 370 patients with ovarian tumors were divided into three groups. The groups were classified as serous cystadenoma, serous BOT and HGSOC. The potential association of preoperative hemoglobin insert ignore into journalissuearticles values(Hb);, red cell distribution width insert ignore into journalissuearticles values(RDW);, Hb/RDW ratio, ratio of neutrophils to lymphocytes insert ignore into journalissuearticles values(N/L); and ratio of platelets to lymphocytes insert ignore into journalissuearticles values(P/L); were analyzed. Results: P/L and N/L were significantly lower in benign serous cystadenoma or serous BOT than HGSOC insert ignore into journalissuearticles values(p<0.001 and p<0.001);. Benign serous cystadenoma was significantly associated with lower median RDW compared to serous BOT and HGSOC insert ignore into journalissuearticles values(p<0.001);. Hb/RDW ratio was significantly lowest in patients with HGSOC and significantly highest in patients with benign serous cystadenoma insert ignore into journalissuearticles values(p<0.001);. Conclusion: Preoperative Hb/RDW can be used as predictor for discrimination of benign serous cystadenoma, serous BOT and HGSOC. N/L and P/L may be considered to distinguish the benign serous cystadenoma and serous BOT from HGSOC.
Keywords : Over kanseri, inflamatuar kan belirteçleri, kırmızı hücre dağılım genişliği RDW,