Evaluation of Fetal Thymus in Pregnancies with Inflammatory Bowel Disease

Authors : Dilek MENEKŞE BEŞER, Dilek SAHİN

Pages : 1910-1914

Doi:10.38136/jgon.1292772

View : 40 | Download : 31

Publication Date : 2023-10-01

Article Type : Research Paper

Abstract :Aim: To investigate the fetal thymic-thoracic ratio in pregnancies complicated with inflammatory bowel diseaseinsert ignore into journalissuearticles values(IBD);. Materials and Method: This case-control study included 26 pregnant women diagnosed with Ulcerative Colitis insert ignore into journalissuearticles values(UC); and Crohn’s Disease insert ignore into journalissuearticles values(CD); and 26 healthy pregnant women at 28-40 gestational weeks. The control group was selected from uncomplicated pregnancies matched by gestational age. Demographic characteristics, disease type, and disease activity were assessed after ultrasonographic evaluation. The thymic-thoracic ratio insert ignore into journalissuearticles values(TTR); was calculated by dividing the anteroposterior thymus measurement by the intrathoracic mediastinal diameter. Results: TTR measurements were 0.32±0.02 in the case group and 0.35±0.02 in the control group insert ignore into journalissuearticles values(p <.001);. 34.6% insert ignore into journalissuearticles values(n=9); of the patients in the case group had an attack at least once during pregnancy. There were no significant differences in the median TTR values between UC and CD groups. TTR was significantly decreased in the group who had an attack at least once during pregnancy compared to those who did not insert ignore into journalissuearticles values(0,31 vs. 0,34, respectively, p=.012);. Conclusion: This is the first study to assess the impact of IBD on fetal TTR. Maternal acute and chronic inflammation in pregnancies with IBD may affect the fetal thymus size due to the intrauterine milieu. Considering that exacerbation during pregnancy also affects fetal thymus size, it is crucial to keep these patients in remission throughout the disease and follow up closely.
Keywords : İnflamatuar barsak hastalığı, Ülseratif Kolit, Crohn hastalığı, Fetal timus, Timik torasik oran