Comparison of first and third trimester complete blood count parameters for prediction of preterm birth

Authors : Engin YURTÇU, Hatice ÖZKUL, Vehbi Yavuz TOKGÖZ, Betül KEYİF

Pages : 1833-1839

Doi:10.38136/jgon.1316779

View : 51 | Download : 45

Publication Date : 2023-10-01

Article Type : Research Paper

Abstract :Introduction: The complete blood count parameters and its combinations, such as neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, platelet-lymphocyte ratio insert ignore into journalissuearticles values(PLR);, and mean platelet volume insert ignore into journalissuearticles values(MPV);, are inflammatory markers. In this study, we aimed to demonstrate the possible role of complete blood count parameters insert ignore into journalissuearticles values(NLR, PLR, and MPV); in predicting preterm birth. Material and Methods: The complete blood count parameters in the first and third trimesters were recorded, as well as the corresponding NLR, PLR, and MPV. The study population was categorized as preterm insert ignore into journalissuearticles values(n = 94); and term births insert ignore into journalissuearticles values(n = 953);. The preterm birth group was further divided into early preterm insert ignore into journalissuearticles values(n = 11); and late preterm birth insert ignore into journalissuearticles values(n = 83); groups. The inflammatory markers were compared between the study groups for the first and third trimesters separately. The alterations between the first and third trimester values were also compared. Results: The first trimester values were similar across the study groups. Moreover, the MPV difference between the first and third trimesters was significantly lower in the preterm group than in the term group insert ignore into journalissuearticles values(0.0  1.1 vs. 0.2  1.1, p = 0.038);. Furthermore, NLR values were higher in the early preterm subgroup than in the late preterm and term groups for the first and third trimesters insert ignore into journalissuearticles values(first trimester; 4.0  1.2 vs. 3.1  2.0 and 3.1  1.3, p = 0.005; third trimester; 5.3  1.2 vs. 4.0  1.5 and 4.4  2.9, p = 0.013);. Conclusion: NLR and MPV predict preterm births in the first trimester and before birth. This enables physicians to take some precautions in preventing preterm delivery.
Keywords : Tam kan sayımı parametreleri, nötrofil lenfosit oranı, ortalama trombosit hacmi, preterm doğum, erken preterm doğum