Evaluation of Prenatal Invasive Testing Complications in a Tertiary Care Centre

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Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
Cilt: 22 Sayı: 2
Evaluation of Prenatal Invasive Testing Complications in a Tertiary Care Centre

Evaluation of Prenatal Invasive Testing Complications in a Tertiary Care Centre

Authors : Zafer Bütün, Masum Kayapınar, Ece Akça Salık, Gökalp Şenol, Kamuran Suman

Pages : 163-169

Doi:10.38136/jgon.1565583

View : 47 | Download : 21

Publication Date : 2025-06-30

Article Type : Research Paper

Abstract :Aim: Invasive tests such as amniocentesis or chorionic villus sampling (CVS) are associated with an increased risk of miscarriage, testing should be done with caution in pregnancies considered to be at high risk for aneuploidies and other genetic disorders. The aim of our study is to present the complications that develop after invasive prenatal tests such as amniocentesis, cordocentesis and chorionic villus sampling. Methods: A retrospective observational study was conducted covering a period of 3 years and 1 month, involving 282 pregnant women at high risk of genetic disorders who underwent invasive prenatal testing such as chorionic villus sampling, amniocentesis, or cordocentesis. Results: A statistically significant difference was found in at least one group in terms of gestational age at delivery, birth weight, current week and pregnancy risk among amniocentesis, cvs and cordocentesis groups (p<0.05). The average birth weight of the amniocentesis group (3099.04 ± 688.21) was found to be higher than the cvs group (2172.42 ± 1551.06). The risk of screening test among CVS, amniocentesis (0.0038±0.0063) and cordocentesis groups (0.001±0.0023) was found to be higher than the cvs (0.0058±0.0061) group. The rate of USG anomaly in the Cordocentesis group (73.2%) was found to be different from the Amniocentesis group (42.8%) and CVS group (12.1%). The rate of termination was found to be higher in the CVS (33.3%) and cardocentesis (31.7%) groups compared to the Amniocentesis (4.3%) group. Conclusion: Complication rates including Bleeding, Redness at the wound site, bradycardia, amniotic fluid leakage, chorioamnionitis, miscarriage were similar among group.
Keywords : Amniosentez, Koryon villus biyopsisi, Kordosentez, Prenatal invaziv test, Komplikasyon

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