SHORT TERM EFFECTIVENESS OF LOCAL AUTOLOGICAL PLATELET-RICH PLASMA (PRP) INJECTION IN THE TREATMENT OF WOMEN WITH STRESS URINARY INCONTINENCE

Authors : Semih Sezgin, Ali Hakverdi, Ahmet Beyazıt

Pages : 311-315

Doi:10.38136/jgon.1357754

View : 27 | Download : 42

Publication Date : 2025-09-30

Article Type : Research Paper

Abstract :ABSTRACT Aim: We aimed to evaluate the short term efficacy of periurethral autolog plasma rich plasma (PRP) as an alternative to surgical treatment in women with stress urinary incontinence. Materials and Methods: Thirty-six patients diagnosed with SUI and Stress-weighted Mixed Incontinence, determined by Urodynamics, participated in the study. PRP was applied to the patients at the beginning and at the end of the first month. The efficacy of the treatment was evaluated by quality of life questionnaires and the cough-stress test (CST) to the patients at the beginning, the 1st month and the 3rd month after the procedure. Results: In the ICIQ-SF questionnaire, the preoperative mean score was 15.36± 3.53 decreased to 10.53±3.52 at the end of the 3rd month (p<0,001). It was observed that the initial value of the UDI-6 questionnaire, decreased from 11.33±3.64 to 8.25±3.34 at the end of the 3rd month(p<0,001). In the IIQ-7 test a decrease was observed from 12.50±4.95 to 8.94±4.34, and a significant improvement was detected in all questionnaires compared to pre-procedure (p<0.001). Of 35 patients with positive CST at the beginning, 14 of them were negative (40%) at the end of the 3rd month, and a significant difference was detected. (p<0.001). Conclusıon: It has been observed that PRP application can be an alternative to invasive surgery in the short term treatment of SUI incontinence. Although PRP seems to be an appropriate treatment with its cost-effective, short application time, and less side-effect profile, more patients and longer-term studies are needed.
Keywords : Stres Üriner İnkontinans, PRP, Periüretral Enjeksyon

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