Luteal Phase Support in IUI: A Game-Changer for Pregnancy Outcomes?

Home Page
About
Submit A Journal
Submit A Conference
Submit Paper/Book
- Submit a Preprint
- Submit a Book
Contact

Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
Cilt: 22 Sayı: 3
Luteal Phase Support in IUI: A Game-Changer for Pregnancy Outcomes?

Luteal Phase Support in IUI: A Game-Changer for Pregnancy Outcomes?

Authors : Uğurcan Zorlu, Batuhan Turgay, Mohammad İbrahim Halilzade, Mert İshak Kaya, Özlem Moraloğlu Tekin

Pages : 387-392

Doi:10.38136/jgon.1724658

View : 37 | Download : 73

Publication Date : 2025-09-30

Article Type : Research Paper

Abstract :Aim: This study aims to evaluate the impact of luteal phase support (LPS) with progesterone on pregnancy and live birth rates in patients undergoing intrauterine insemination (IUI) treatment. Materials and Methods: A retrospective analysis was conducted on 88 patients who underwent IUI treatment at a tertiary center between 2019 and 2021. Patients were divided into two groups: Group 1 (n=49) received progesterone for luteal phase support, while Group 2 (n=39) did not receive any luteal support. Clinical, demographic, and biochemical parameters, including age, BMI, infertility duration, and ovarian reserve markers, were compared between the two groups. Treatment outcomes such as pregnancy rates, clinical pregnancy, and live birth rates were analyzed. Results: No significant differences were observed between Group 1 and Group 2 in terms of demographic characteristics (age, BMI, and infertility duration) or biochemical markers (AMH, FSH, estradiol, and progesterone). The pregnancy rate in Group 1 was 14.2%, compared to 12.8% in Group 2 (p=0.640). Live birth rates were also similar between the groups (12.2% in Group 1 vs. 10.2% in Group 2, p=0.510). Treatment parameters, including endometrial thickness and gonadotropin dosage, showed no significant differences. Conclusion: Progesterone supplementation for luteal phase support did not significantly improve pregnancy or live birth rates in IUI patients. These findings suggest that luteal phase support may not be necessary in routine IUI cycles, particularly when standard ovulation induction protocols are followed. Further research is needed to clarify its role in specific patient populations.
Keywords : luteal faz desteği, progesteron, IUI, gebelik oranı, canlı doğum oranı.

ORIGINAL ARTICLE URL

* There may have been changes in the journal, article,conference, book, preprint etc. informations. Therefore, it would be appropriate to follow the information on the official page of the source. The information here is shared for informational purposes. IAD is not responsible for incorrect or missing information.