Inflammation in Chronic Psychiatric Patients: Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume

Authors : Figen UNAL DEMİR, Filiz ÖZSOY, Esma AKPINAR ASLAN

Pages : 53-59

Doi:10.17517/ksutfd.1127281

View : 88 | Download : 86

Publication Date : 2023-07-12

Article Type : Research Paper

Abstract :Objective: The aim of this study was to examine the Neutrophil/Lymphocyte Ratio insert ignore into journalissuearticles values(NLR);, Platelet/Lymphocyte Ratios insert ignore into journalissuearticles values(PLR);, and Mean Platelet Volume insert ignore into journalissuearticles values(MPV);, red blood cell distribution width insert ignore into journalissuearticles values(RDW); and leukocyte cell levels of inpatients with mental illness by comparing them with each other and healthy controls. Materials and Methods: A total of 600 people were included in our study, 500 of whom were taken as the patient and 100 as the control group. The diagnosis of patients according to DSM-5-Criteria were 34.8% Schizophrenia, 21% had Generalized-Anxiety-Disorder, 14.4% had Bipolar-Affective-Disorder, 14% had Major-Depressive-Disorder, 7.2% had Adjustment-Disorder, 4.2% had Schizoaffective-Disorder, 3.6% had other psychiatric illnesses. Results: It was seen that hemoglobin, platelet, monocyte, blood platelet distribution insert ignore into journalissuearticles values(PCT);, percentage account of RDW insert ignore into journalissuearticles values(RDW-CV); did not have statistically significant differences between groups insert ignore into journalissuearticles values(p values were 0.082, 0.214, 0.526, 0.082, 0.771, respectively);. The lymphocyte, eosinophil, basophil, MPV, standard deviation of RDW insert ignore into journalissuearticles values(RDW-SD); were higher compared with healthy controls insert ignore into journalissuearticles values(p values were 0.002, 0.003, <0.001, <0.001, 0.003, 0.003, respectively);. NLR and PLR were low in the patient group compared to healthy controls insert ignore into journalissuearticles values(p<0.001);. Conclusion: It was found that some of the inflammation parameters of chronic with mental illness were different from those of healthy controls. However, further prospective studies are needed to better reveal the relationship between inflammatory parameters and mental illnesses..
Keywords : İnflamasyon, nötrofil lenfosit oranları, platelet lenfosit oranları, şizofreni, bipolar bozukluk

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