Clinical Significance of CRP/Albumin Value on Hospitalization and Length of Hospital Stay of Patients with Coronavirus-19: A Prospective Study

Authors : Uğur LÖK, Umut GÜLAÇTI, Hüseyin KAFADAR, Hakan KAYA

Pages : 99-105

Doi:10.17517/ksutfd.1222637

View : 39 | Download : 76

Publication Date : 2023-07-12

Article Type : Research Paper

Abstract :Objective: To investigate the diagnostic and prognostic significance of the C-reactive protein-to-albumin ratio insert ignore into journalissuearticles values(CAR); in coronavirus disease 2019 insert ignore into journalissuearticles values(COVID- 19); patients admitted for the first time to a hospital emergency department insert ignore into journalissuearticles values(ED);. Materials and methods: The study we report herein was a single-center, prospective observational study. A total of 745 participants insert ignore into journalissuearticles values(385 patients, 360 individuals); were included in the study. The CAR was calculated by dividing the C-reactive protein insert ignore into journalissuearticles values(CRP; mg/L); value by the albumin value insert ignore into journalissuearticles values(gr);. The data were analyzed using MedCalc Statistical Software v12.7.0.0 insert ignore into journalissuearticles values(Ostend, Belgium); and Student’s t-test, chi square test, and Pearson’s correlation coefficient. A p-value of <0.05was considered statistically significant. Results: A total of 355 patients were hospitalized, and 30 of them were followed as outpatients. The mean CAR values of the hospitalized patients and the outpatients were 0.34±0.89 and 0.39±0.72 respectively insert ignore into journalissuearticles values(95% confidence interval [CI]: -0.31 to 0.40; p=0.796);. A 309 patients were hospitalized in wards and 46, in intensive care units; their mean CAR values were 0.33±0.92 and 0.44±0.74, respectively insert ignore into journalissuearticles values(95% CI: -0.17 to 0.39; p=0.449);. As the CAR value increased, the length of hospital stay also increased insert ignore into journalissuearticles values(p<0.0001);. At the best cut-off point for COVID-19 diagnosis, CAR was shown to have 82.66% specificity, 69.72% sensitivity, 4.02 positive likelihood, and 0.37 negative likelihood. Conclusion: The length of stay in the hospital of the COVID-19 patients in the study was closely related to their CAR values obtained at the time of their first ED admission.s closely related to their CAR values obtained at the time of their first ED admission.
Keywords : Coronavirus disease 2019, C reactive protein to albumin ratio, first admission, hospital stay, Coronavirüs hastalığı 2019, C reaktif protein albümin oranı, ilk başvuru, hastanede kalış süresi