Mesenchymal stem-cell derived treatment in osteosarcoma between 1993-2023: Bibliometric study

Authors : Akif Mirioğlu

Pages : 71-77

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Publication Date : 2025-03-24

Article Type : Research Paper

Abstract :Objective: Osteosarcoma is a malignant bone tumor with a high incidence in adolescence and childhood. Treatment is long and difficult, including chemotherapy, radiotherapy, and orthopedic surgery. Stem cell-derived treatment has also recently been studied in osteosarcoma. In this bibliometric study, we aimed to illuminate the trend of research between osteosarcoma and stem cell-derived treatment. Materials and Methods: Publications on osteosarcoma were retrieved from the Web of Science Core Collection. R studio software and the VOS viewer analysis program were used for data analysis. Results: There were 853 publications with an average of 7.7 publications per year. The most productive countries were the USA and China respectively. According to the categorical classification described in the WoS, oncology (41.7%), and cell biology (18.1%) were the first two fields in terms of diagnosis and treatment, while pathology (3.7%) and orthopedics (2.2%) had lower levels of work. However, the most cited author locally was Gibbs from the University of Florida University of Alberta UF Orthopedic & Sports Med Inst. in the USA. The keywords “cancer stem cell”, “bone cancer”, and “mesenchymal stem cell” had been determined to have strong links to osteosarcoma. Cancer Res was the most cited journal. Conclusion: As a result, it has been found that research presenting strong links to the relationship between cell-derived therapy and osteosarcoma has shown an increase in recent years.
Keywords : Osteosarcoma, kök hücre, bibliyometri