Evaluation of Sputum Eosinophil Level and Presence of Charcot-Leyden Crystals in Patients with Airway Hyperreactivity

Authors : Sümeyra Alkış Koçtürk, Hatice Şahin

Pages : 194-198

Doi:10.17517/ksutfd.1578552

View : 63 | Download : 296

Publication Date : 2025-11-22

Article Type : Research Paper

Abstract :Aim: The focus of this research is to clarify whether eosinophilia is an independent factor in causing bronchial hyperreactivity or if its presence in sputum plays a supplementary role in this condition; especially in asthma. Material and Methods: Data was obtained from a sample of 100 individuals in the respiratory care unit, concentrating on cases characterized by bronchial hyperreactivity. We made three groups with 30 asthmatics, 34 non-asthmatic respiratory disease group and 36 control group patients. We decided to get the patients’ sputum when they were internalized first. Eosinophilia can therefore occur in addition to pre-existing illnesses. Results: To explain; we defined the ratio of eosinophilia in three groups and also searched the presence of Charcoat-Leyden crystals out of smear examination. The results of the study demonstrate eosinophilia ratio among asthmatics was more prominent (16.6%) replicating past findings. Results from the non-asthmatic patient group confirm that percentage of patients with eosinophilia was lesser than asthmatics (13.3%). Consistent with hypotheses, control group had the least percentage (8.8%). Conclusion: The study examined the relation between eosinophilia and presence of Charcoat Leyden crystals. Despite our efforts, we were unable to observe any signs of coexistence, as no crystal structures were detected in any of the smears examined.
Keywords : astım, eosinofili, bronşiyal hiperreaktivite

ORIGINAL ARTICLE URL