FRACTURES OF PREMATURITY AND ASSOCIATED FACTORS: A CASE-CONTROL STUDY

Authors : Sinem Yalnızoğlu Çaka, Sümeyra Topal, Selin Aytemiz, Sadık Yurttutan
Pages : 317-325
Doi:10.18229/kocatepetip.1600431
View : 40 | Download : 48
Publication Date : 2025-10-13
Article Type : Research Paper
Abstract :OBJECTIVE: The processes experienced by preterm neonates at birth and after birth may affect skeletal growth and bone mineralization. This study aims to evaluate the fractures occurring in premature infants admitted to the Neonatal Intensive Care Unit and to investigate the relationship with some characteristics. MATERIAL AND METHODS: This retrospective study is a case-control study conducted in preterms born at ≤ 36+6 weeks gestational age admitted to the Neonatal Intensive Care Unit between 2012 and 2022. The sample comprised 78 preterm births (39 cases and 39 controls). Birth records and clinical follow-ups (laboratory results, congenital diseases, parenteral nutrition, respiratory support, etc.) until the postnatal discharge process that may be related to fracture were analyzed. RESULTS: The prevalence of fractures in premature infants was found to be 0.94%. The fracture site of 26.9% (n=21) of the participants was the humerus and the mean time to fracture was 21.18±23.68 days. It was found that preterms in the case group had lower APGAR scores and longer total parenteral nutrition, mechanical ventilation and hospitalization times compared to the control group and the difference was statistically significant (p<0.05). In addition, some laboratory results (Phosphorus, Parathormone, etc.) levels of preterms showed significant differences between the groups (p<0.05). Genetic congenital anomaly, cholestasis and sepsis increased the case status 32.764, 21.782 and 0.051 times, respectively (p<0.05). It appears that the incidence of fractures in premature infants who are breastfed is 0.108 times less than in those who are not breastfed. Total parenteral nutrition duration variable decreases the effect of the presence of breast milk. CONCLUSIONS: Identifying and recognizing the risk factors for fractures and providing appropriate treatment and care will reduce fracture rates in premature infants.
Keywords : Kemik hastalıkları, kırık, hemşirelik bakımı, prematüre

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