Correlation Between HOMA-IR and eGFR Values

Authors : Mehmet ÖZDİN, Durhasan MUNDAN

Pages : 17-24

View : 52 | Download : 16

Publication Date : 2022-12-29

Article Type : Research Paper

Abstract :Objective: The aim of this study is to determine the correlation between the homeostatic model assessment of insulin resistance insert ignore into journalissuearticles values(HOMA-IR); values and the estimated glomerular filtration rate insert ignore into journalissuearticles values(eGFR); values of individuals who applied to different polyclinics of a training and research hospital with different complaints. Materials and Methods: In the study, the data of 7815 insert ignore into journalissuearticles values(1740 men and 6075 women); patients who applied to different polyclinics were analyzed. Adult patients who met the study criteria and requested HOMA-IR and eGFR were identified by the hospital information management system. Age and gender of all patients were determined. The data were evaluated statistically. Insulin resistance; was measured by the homeostatic model evaluation method. Results: The mean HOMA-IR and eGFR values of the patients were 3.28±0.52 and 111.35±22.91, respectively. While HOMA-IR values were found to be higher than normal in 60% of 7815 patients, the eGFR values of the same patients were found to be lower than normal. There was a moderate negative correlation between HOMA-IR and eGFR insert ignore into journalissuearticles values(r = -0.48);. In other words, it was determined that patients with increased HOMA-IR values had a moderate decrease in eGFR values. Conclusion: There was a moderate negative correlation between HOMA-IR and eGFR However, it will be important to make this information available to clinicians with a more detailed study. Evaluation of HOMO-IR and eGFR levels can be utility for early diagnosis in the development and follow up of insulin resistance and kidney disorders.
Keywords : HOMA IR, eGFR, Korelasyon

ORIGINAL ARTICLE URL