A case report of Glanzman Thrombasthenia with anterior mediastinal hematoma and Factor V Leiden mutation

Authors : Hüseyin TOKGÖZ, Ümran ÇALIŞKAN, Tuğçe DURAN, Kaniye Zeynep ÇALIŞKAN SAK

Pages : 17-22

Doi:10.59244/ktokusbd.1173506

View : 43 | Download : 64

Publication Date : 2023-04-28

Article Type : Other Papers

Abstract :Glanzmann thrombasthenia insert ignore into journalissuearticles values(GT); is an autosomal recessive disease associated with platelet aggregation dysfunction with normal platelet count, causing bleeding diathesis. GT is characterized by decreased levels or decreased function of the glycoprotein IIb-IIIa insert ignore into journalissuearticles values(GPIIb-IIIa); complex and therefore results in an increased tendency to bleeding as the aggregation phase of primary hemostasis cannot be sufficiently formed. Factor V Leiden mutation is a genetic mutation predisposing to thrombophilia. We present this case in which Factor V and Glanzmann thrombasthenia with hematoma in the anterior mediastinum are rarely seen together.
Keywords : Factor V Leiden, Glanzmann trombasteni, Hematom, Trombofili