Current Median Values of Double and Triple Screening Test Parameters for Antalya Region

Authors : Sibel Kulaksızoğlu, Nazife Öztürk, Ferda Işıkçelik, Meliha Meliş Günaltay

Pages : 22-28

Doi:10.35514/mtd.2025.123

View : 88 | Download : 73

Publication Date : 2025-08-31

Article Type : Research Paper

Abstract :Objective: The study aims to ascertain the regional medians of the double and triple screening test parameters in the Antalya region\\\'s population, thereby providing significant insights into prenatal care and public health. Material and Methods: The study, meticulously conducted with pregnant women who applied to the Antalya Training and Research Hospital\\\'s labs, involved the calculation of the Median for alpha-fetoprotein (AFP), beta-human chorionic gonadotropin (β-hCG), unconjugated estriol (uE3), plasma protein-A (PAPP-A), and free beta-human chorionic gonadotropin (β-hCG). Results: Compared with other years, the median value computed for fß-hCG in 2022 was lower, whereas the median value calculated for 2020 was greater. The median value computed for PAPP-A in 2022 was found to be lower than previous years, similar to the finding for fß-hCG, and the median value calculated for 2020 was found to be greater than other years. The newly calculated AFP median value peaked in 2018 and decreased in 2022. Conclusion: It was observed that the median value calculated for ß-hCG for 2020 was more significant than that estimated for other years and that the median value for 2022 was lower than that for other years. The newly calculated median value of uE3 was the highest in 2018 and the lowest in 2022. Regional median values of prenatal screening tests should be updated at regular intervals. In particular, it is essential to develop awareness-raising policies to disseminate prenatal screening tests and to consider biological variability in these tests.
Keywords : Noninvaziv prenatal test, prenatal tarama, tarama

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