Late Termination of Pregnancy: A Retrospective Evaluation of 243 Pregnancies In A Tertiary Medical Center

Authors : Emine Kirtiş, Gül Alkan Bulbul, Hülya Kandemir, Cem Yaşar Sanhal, Tuba Metin, İnanç Mendilcioğlu
Pages : 157-163
Doi:10.53394/akd.1345750
View : 107 | Download : 83
Publication Date : 2025-05-28
Article Type : Research Paper
Abstract :Objective: This study aims to assess changes in the indications for late termination of pregnancy performed after 24 weeks of gestation over the years. Material and Methods: We performed a retrospective analysis of a cohort who requested late termination of pregnancy after a diagnosis of fetal abnormality at the Department of Obstetrics and Gynecology, Akdeniz University Faculty of Medicine, between January 2007 and December 2022. The cases were divided into two groups with 8-year time intervals: Group 1 spanning from January 2007 to December 2014, and Group 2 spanning from January 2015 to December 2022. Results: A total of 243 cases were evaluated in the analysis, with 127 (52.3%) cases in Group 1 and 116 (47.7%) cases in Group 2. Over the past sixteen years, the most frequent reasons for late termination of pregnancy involving fetuses were central nervous system malformations (43.2%), cardiovascular system anomalies (17.3%), and chromosomal abnormalities (11.1%). A significant increase was noted over the course of time in the percentage of instances presenting cardiovascular system anomalies and chromosomal abnormalities (p<0.05). Conclusion: This analysis provides insight into the causes of late termination of pregnancy. Especially in the third trimester, central nervous system anomalies are an important cause of late termination of pregnancy. In addition to standard second-trimester anatomical scanning, limited first-trimester anatomical scanning and third-trimester neurosonogram will contribute to the diagnosis of fetal anomalies. In conclusion, expanding screening strategies will also reduce the need for late termination of pregnancy due to fetal abnormalities.
Keywords : Konjenital malformasyon, fetal ölüm, fetisit, gebeliğin sonlandırılması

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