Antioxidant effects of curcumin on the blood tissue in rats

Authors : Şevkinaz KONAK, Emine Hilal ŞENER

Pages : 8-14

Doi:10.24998/maeusabed.539891

View : 25 | Download : 13

Publication Date : 2019-06-30

Article Type : Research Paper

Abstract :Curcumin is a pigment found in Indian saffron spices, also known as turmeric. The aim of this study is to investigate the antioxidant effect of curcumin, a phytochemical, on the blood tissue of rats. In the study, 24 Wistar rats were 8 weeks old, randomly divided into 2 groups which were the control group and the experimental group was fed with curcumin supplement. Curcumin supplemented group was fed at 300mg/kg/day curcumin dissolved in corn oil by oral gavage for 12 days. 24 hours after the last feeding, TAC insert ignore into journalissuearticles values(Total Antioxidant Capacity); and TOC insert ignore into journalissuearticles values(Total Oxidant Capacity);  were analyzed in blood samples. In curcumin supplemented group TAC decreased significantly than control group insert ignore into journalissuearticles values(p<0,05);. When the TOC is examined, in curcumin supplemented group TOC was evaluated statistically higher than in the control group insert ignore into journalissuearticles values(p<0,05);. Results of the study show that curcumin strengthens the antioxidant defense system. 
Keywords : Curcumin, blood tissue