Effect of Combination of Hypericum perforatum, Calendula officinalis and Aloe vera Plant Extracts on Incisional Wound Healing

Authors : Sultan KAYA, Şevkinaz DOĞAN, Mahmut ATEŞ

Pages : 161-168

Doi:10.24998/maeusabed.1195179

View : 151 | Download : 220

Publication Date : 2022-12-31

Article Type : Research Paper

Abstract :Today, patients and health professionals are turning to innovative approaches due to the lack of success in treating chronic wounds. This study aimed to investigate the effect of a mixture of Hypericum perforatum histopathologically, Calendula officinalis, and Aloe vera plant extracts on incisional wound healing. A total of 14 rats, 7 rats, were used in each group. The groups were divided into experimental and control. While daily wound care was performed with an herbal extract mixture in the experimental group, sterile saline was used for daily wound care in the control group. During the study, wound surface area measurement, macroscopic evaluation, and histopathological examination were performed in both groups. According to research findings, the control group\`s wound-healing process is shorter. Histopathological analyses revealed that wound healing was completed on day 21.
Keywords : Aloe vera, Calendula officinalis, Hypericum perforatum, İnsizyonel yara, Yara iyileşmesi