Clinical, Radiological and Histopathological Characteristics of Unilateral Sinonasal Lesions: An 8-Year Retrospective Study of 202 Patients

Authors : Furkan Yavuz, Kerimcan Çakıcı, Sabri Köseoğlu

Pages : 229-236

Doi:10.47572/muskutd.1725596

View : 62 | Download : 125

Publication Date : 2025-12-29

Article Type : Research Paper

Abstract :Unilateral sinonasal pathologies encompass a wide spectrum of conditions ranging from benign inflammatory lesions to rare malignancies, often posing diagnostic challenges due to their ability to mimic innocuous entities while potentially harboring aggressive disease. In this retrospective study conducted at a tertiary otorhinolaryngology center in southwestern Turkey, the epidemiological and histopathological characteristics of 202 adult patients who underwent surgical excision of unilateral sinonasal masses between January 2017 and January 2025 were analyzed. Patients with bilateral disease, previous biopsies at external centers, or incomplete medical records were excluded. The mean patient age was 48.1 ± 17.4 years, with a male predominance of 65.8%. The most prevalent diagnosis was inflammatory polyp or chronic inflammation (57.4%), followed by inverted papilloma (16.8%) and antrochoanal polyp (11.4%), while fungal pathologies, including allergic fungal rhinosinusitis and fungus ball, accounted for 6% of cases. Malignancies were identified in three patients (1.5%). Although computed tomography demonstrated bone erosion or destruction in 17.3% of cases, the majority of these lesions were benign. Nasal obstruction emerged as the most common presenting symptom, noted in 79.7% of patients. The findings emphasize that while most unilateral sinonasal pathologies are benign, the relatively high frequency of inverted papillomas and fungal lesions necessitates meticulous clinical and radiological assessment, with histopathological confirmation remaining indispensable for definitive diagnosis. These region-specific data offer valuable insight into the epidemiology of unilateral sinonasal pathologies and may inform future multicenter investigations aimed at enhancing diagnostic accuracy and treatment strategies.
Keywords : İçeri Dönük Papillom, Nazal Polipler, Türkiye, Tek Taraflı Nazal Obstrüksiyon

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