Predictive Role of Halp Score, LCR Value and CRP-Albumin Ratio for Survival and Recurrence in Gastric Cancer

Authors : Adem Şentürk, Ahmet Tarık Harmantepe, Emre Gönüllü, Alp Ömer Cantürk, Fuldem Mutlu, Metin Ercan

Pages : 153-161

Doi:10.26453/otjhs.1663269

View : 55 | Download : 45

Publication Date : 2025-06-30

Article Type : Research Paper

Abstract :Objective: To investigate whether the ratios of biochemical markers such as hemoglobin, albumin, lymphocyte and platelet (HALP) score, lymphocyte-C-reactive protein ratio (LCR) and CRP/Albumin ratio can predict the survival and recurrence of the disease in gastric cancer patients. Materials and Methods: Adult patients who were operated for gastric cancer in our clinic between January 2014 and December 2023 (n: 85) were included in this retrospective study. HALP and CRP/Albumin scores and LCR ratios were calculated from the preoperative biochemical data of the patients. Results: Overall survival of patients with a low HALP score was significantly shorter than that of patients with a high HALP score (30.6 vs 35.5 months) (p<0.05). In addition, overall survival of patients with low LCR rate was significantly shorter than that of patients with high LCR score (27.9 vs 35.6 months, p<0.05), and similarly, the overall survival of patients with low CRP/Albumin value was significantly shorter than that of patients with high CRP/Albumin value (29.9 months vs 32.4 months) (p<0.05). There was a strong correlation between HALP, LCR, and CRP/Albumin scores and recurrence (for each p<0.05). According to the results of multivariate Cox regression analysis, HALP score, LCR score and CRP/albumin ratio were found to be independent and positive factors for overall survival (p<0.05). Conclusions: Low scores in any of the HALP, LCR, and CRP/Albumin scores were associated with poor postoperative overall survival and recurrence in patients with gastric cancer.
Keywords : Biyobelirteçler, mide kanseri, prognoz, nüks

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