Identifying Predictors of Early Rebleeding Following Transcatheter Embolization in Acute Non-Variceal Upper Gastrointestinal Bleeding: A Retrospective Analysis

Authors : Ali Dablan, Yusuf Bahtiyar Uluman, Tevfik Güzelbey, Mehmet Cingöz, Erdem Kınacı, Özgür Kılıçkesmez

Pages : 556-566

Doi:10.20515/otd.1578761

View : 41 | Download : 10

Publication Date : 2025-06-18

Article Type : Research Paper

Abstract :Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is a critical medical emergency. While transcatheter arterial embolization (TACE) is increasingly utilized when endoscopic hemostasis fails, the risk factors for early rebleeding post-TACE remain unclear. This study aimed to identify predictors of early rebleeding within 30 days of TACE in refractory ANVUGIB cases. A retrospective analysis was conducted on 56 TACE procedures performed between June 2020 and June 2023. Patients were included based on strict criteria, including failed endoscopic hemostasis or unsuitability for endoscopy. We assessed variables associated with early rebleeding and conducted univariate and multivariate analyses to identify significant predictors. Despite a technical success rate of 100%, 39.3% of patients experienced early rebleeding. Significant predictors of rebleeding included delayed angiography (P = 0.023), comorbidities (P = 0.048), failed endoscopic hemostasis (P = 0.010), and embolization of multiple vascular territories (P = 0.012). Timely angiographic embolization is essential for effective bleeding control in ANVUGIB. Delayed angiography, presence of comorbidities, failed endoscopic hemostasis, and embolization of multiple vascular territories were identified as significant predictors of early rebleeding. These findings highlight the importance of early and targeted intervention to improve clinical outcomes.
Keywords : Üst gastrointestinal kanama, Endoskopi, Anjiyografi, Embolizasyon

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