Synthesis, structural studies and antioxidant activities of M(II) complexes with NOS donor schiff base ligand

Authors : Nevin TURAN, Mustafa BİNGÖL, Ahmet SAVCI, Enver Fehim KOÇPINAR, Naki ÇOLAK
Pages : 279-289
View : 33 | Download : 7
Publication Date : 2021-09-27
Article Type : Other Papers
Abstract :Schiff base ligand, insert ignore into journalissuearticles values(E);-methyl 6-acetamido-2-insert ignore into journalissuearticles values(5-bromo-2-hydroxybenzylideneamino);-4,5,6,7- tetrahydrobenzo[b]thiophene-3-carboxylate, was successfully prepared with condensation reaction. The newly obtained Schiff base used to synthesize five new complex, [FeLClinsert ignore into journalissuearticles values(H2O);2]∙1.5H2O, [CoLClinsert ignore into journalissuearticles values(H2O);2]∙2H2O, [NiLClinsert ignore into journalissuearticles values(H2O);2]∙H2O, [RuLClinsert ignore into journalissuearticles values(p-cymene);]∙3.5H2O and [PdLCl∙H2O]∙ 3H2O. From the magnetic and spectral data, the geometric structures of these complexes were found to be square planar and octahedral. The characterizations of ligand and complexes were done by FT-IR, UV-Vis, 1H and 13C-NMR, microanalyses, magnetic susceptibility, mass spectra and thermogravimetry analysis insert ignore into journalissuearticles values(TGA); and further were screened for antioxidant activities. Antioxidant properties of synthesized compounds were examined using different methods including total antioxidant activity, FRAP insert ignore into journalissuearticles values(ferric reducing antioxidant power);, CUPRAC insert ignore into journalissuearticles values(cupric reducing antioxidant capacity); and DPPH insert ignore into journalissuearticles values(2,2-diphenyl-1-picrylhydrazyl);. The Ruinsert ignore into journalissuearticles values(II);, Pdinsert ignore into journalissuearticles values(II);, Feinsert ignore into journalissuearticles values(II); and Coinsert ignore into journalissuearticles values(II); metal complexes generally exhibited good antioxidant properties.
Keywords : Biological activity, Transition metal complexes, NOS donor schiff base, Spectral properties

ORIGINAL ARTICLE URL