SYNTHESIS OF BROMINATED QUINOLINES

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Sigma Mühendislik ve Fen Bilimleri Dergisi
Volume:33 Issue:1
SYNTHESIS OF BROMINATED QUINOLINES

SYNTHESIS OF BROMINATED QUINOLINES

Authors : Salih ÖKTEN, Dilek EYİGÜN, Osman ÇAKMAK

Pages : 8-15

View : 42 | Download : 9

Publication Date : 2015-03-01

Article Type : Research Paper

Abstract :In this study, bromination reactions of 1,2,3,4-tetrahydroquinoline by molecular bromine and aromatization reactions of brominated tetrahydroquinolines were reinvestigated. Optimal reaction conditions were established for 6-Bromo-1,2,3,4-tetrahydroquinoline insert ignore into journalissuearticles values(6-BrTHQ ); and 6,8-dibromo-1,2,3,4-tetrahydroquinoline insert ignore into journalissuearticles values(6,8-diBrTHQ);. Improved yields and more shortened reaction times were described for the conversion of 6-BrTHQ and 6,8-diBrTHQ into 6-bromoquinoline and 6,8-dibromoquinoline.
Keywords : Quinoline, tetrahydroquinoline, bromoquinoline, bromination, aromatization, DDQ

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