Clinical Characteristics and Possible Risk Factors of Epilepsy in Children with Cerebral Palsy: A Tertiary-Center Experience

Authors : Didem ARDIÇLI, Özge DEDEOĞLU

Pages : 45-51

Doi:10.12956/tchd.1213912

View : 58 | Download : 12

Publication Date : 2023-01-30

Article Type : Research Paper

Abstract :Objective: The aim of this study was to evaluate the clinical characteristics of children with cerebral palsy insert ignore into journalissuearticles values(CP); and to investigate possible risk factors and prognosis of epilepsy in children with cerebral palsy insert ignore into journalissuearticles values(CP); with a special emphasis on drug-resistant epilepsy insert ignore into journalissuearticles values(DRE);. Materials and Methods: A total of 145 pediatric patients who were followed up with a diagnosis of CP between 2019 and 2022 were evaluated. Demographic features, prenatal/perinatal history, etiology and type of CP, degree of impairment in motor and cognitive functions, seizure type, neuroimaging, and electroencephalography insert ignore into journalissuearticles values(EEG); findings were obtained retrospectively from hospital records. The patients were divided into two groups: CP patients with epilepsy and patients without epilepsy. Study variables were compared between these two groups and also between DRE and controlled epilepsy groups. Results: There were 91 insert ignore into journalissuearticles values(63%); boys and 54 insert ignore into journalissuearticles values(37%); girls with a mean age of 11.1 ± 4.2 years insert ignore into journalissuearticles values(3-18 years);. Epilepsy was present in 107 insert ignore into journalissuearticles values(73.7%); cases and 40.1% of them had refractory epilepsy. Epilepsy was most common in the tetraplegic form of CP insert ignore into journalissuearticles values(p=0.028);. Term gestation, birth weight of ≥2500 g, and history of neonatal seizures were significantly higher in patients with epilepsy insert ignore into journalissuearticles values(p=0.03, 0.01, and 0.03, respectively);. Children with DRE were more likely to have tetraplegic CP insert ignore into journalissuearticles values(50%); and severe intellectual disability insert ignore into journalissuearticles values(56%);. Conclusion: Determination of potential risk factors is important in predicting the development of epilepsy in patients with CP, as it may provide closer follow-up of patients at high risk. Particular attention should be paid to the early identification and treatment of comorbid epilepsy in children with CP.
Keywords : serebral palsi, epilepsi, risk faktörleri, dirençli epilepsi, pediatrik

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