Investigation of the effects of anesthetic inhalation agents with certain biochemical and hematological parameters

Authors : Fatma Arı, Egemen Dere

Pages : 20-33

View : 45 | Download : 14

Publication Date : 2025-06-30

Article Type : Research Paper

Abstract :In this study, the effects of sevoflurane, desflurane and isoflurane on the personnel working in 4 different hospitals were investigated with some biochemical and hematological parameters. A total of 60 anesthesia technicians working in 42 operating rooms were divided into 3 experimental periods, 6-10, 11-15 and 16-20 years, depending on the duration of exposure to the anesthetic agent. 60 individuals with different professions, in the same age range as the experimental group, were selected as the control group. In blood samples, ALT, AST, ALP, CK, LDH, GST and amylase activities and Na+, K+, CK-MB, glucose, urea, total protein, total bilirubin, total cholesterol, triglyceride, leukocyte, erythrocyte and platelet amounts were measured. Although values outside the normal limits were occasionally observed in the 120 individuals studied, the average of all parameters measured for 1 year was found to be within normal values in both the control and experimental groups. Only the enzymes we studied, AST and LDH in women and ALT in men, showed significant results compared to the control group, while Na and K were found to be significant in men (p<0.05).
Keywords : Desflurane, enzyme, isoflurane, sevoflurane, sodium, potassium

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