Evaluation of frontal QRS-T angle and cardiac electrophysiological balance index in patients with coronary artery ectasia

Authors : Pınar Özmen Yıldız

Pages : 1145-1152

Doi:10.17826/cumj.1832176

View : 54 | Download : 162

Publication Date : 2025-12-22

Article Type : Research Paper

Abstract :urpose: The aim of this study was to evaluate arrhythmogenic risk in patients with Coronary artery ectasia (CAE) using the frontal QRS-T (fQRS-T) angle and the index of cardiac electrophysiological balance (iCEB), together with conventional ventricular repolarization parameters. Materials and Methods: This retrospective study included 103 patients who underwent coronary angiography. Individuals with coronary segment dilatation ≥1.5 times the adjacent normal vessel without significant stenosis were classified as the CAE group, while those with angiographically normal coronary arteries comprised the control group. Electrocardiographic (ECG) parameters were analyzed: QT and corrected QT (QTc) intervals, T wave peak-to-end (Tp-e) interval, Tp-e/QT and Tp-e/QTc ratios, fQRS-T angle, and iCEB calculated as QT/QRS; its corrected form (iCEBc) was computed as QTc/QRS. Subgroup analysis compared single-vessel and multivessel ectasia. Results: Patients with CAE demonstrated significantly wider fQRS-T angles (68.0° vs. 22.0°) and higher iCEB (4.39 vs. 4.04) and iCEBc values (4.82 vs. 4.43) compared with controls. QT, QTc, Tp-e, Tp-e/QT, and Tp-e/QTc values were also significantly increased. Multivessel ectasia was associated with a significantly greater fQRS-T angle (84.0° vs. 48.5°) and QTc prolongation (446.6 vs. 414.6 ms). Conclusion: CAE is associated with substantial electrophysiological alterations indicative of heightened arrhythmogenic susceptibility. Increasing anatomical extent further amplifies this burden, particularly as reflected by a wider fQRS-T angle and the global repolarization burden demonstrated by prolonged QTc.
Keywords : Koroner ektazi, elektrokardiyografi, iskemi, repolarizasyon

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