Lung Cancer with Oral Cavity Metastasis: Two Case Reports

Authors : Hakan Yülek, Gaye Keser, Filiz Mediha Namdar Pekiner
Pages : 72-76
Doi:10.29228/erd.74
View : 96 | Download : 81
Publication Date : 2024-08-29
Article Type : Other Papers
Abstract :Invasion and metastasis, which are important biological hallmarks of malignant tumors, are among the most important causes of cancer-related morbidity and mortality. Metastatic tumors in the oral cavity constitute 1-1.5% of oral malignant tumors and the most common primary foci metastasizing to this region are breast, lung, kidney, bone, prostate and colon cancers. The most common site of involvement in the jaw bones is the mandible posterior, while soft tissue involvement is most common in the gingiva. A 63-year-old male patient presented with a mass invading the alveolar bone with irregular and ulcerated areas after extraction of mandibular anterior teeth. Incisional biopsy was performed and histopathological examination of the mass revealed a diagnosis of carcinoma predominantly composed of clear cells. He was referred to the oncology service for investigation of the primary focus and lung cancer was diagnosed by PET-CT scan. A 62-year-old male patient who was diagnosed with lung cancer one year ago and had long bone metastases in his anamnesis presented with pain in the left mandible, which was thought to be caused by the residual tooth root. CBCT examination revealed moth-eaten osteolytic areas in the cortical and trabecular structure involving the inferior alveolar canal in the ramus region of the left mandible. The patient with lung cancer and distant organ metastases was referred to the oncology department and palliative treatment was continued. Both patients died after 3 and 6 months of follow-up. The presence of metastases indicates a poor prognosis and various treatments can be applied according to the stages. Changes occurring in the oral cavity should be followed carefully and diagnosis should be made by histopathological examination when necessary.
Keywords : Oral kavite, oral kanser, akciğer kanseri, histopatoloji, metastaz

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