Comparison Of Biochemical Markers and Insulin Resistance of Polycystic Ovary Syndrome Patients Diagnosed with the Criteria of Rotterdam, Androgen Excess Society and National Institutes of Health

Authors : Pınar KIRICI, Seval Müzeyyen ECİN, Nihal MAVRAL, Sevil ÇİÇEK, Ebru CELİK

Pages : 25-30

Doi:10.52827/hititmedj.1219691

View : 36 | Download : 9

Publication Date : 2023-02-20

Article Type : Research Paper

Abstract :Objective: There are different criteria to diagnose polycystic ovary syndrome insert ignore into journalissuearticles values(PCOS); such as Rotterdam Consensus, Androgen Excess Society insert ignore into journalissuearticles values(AES);, and National Institutes of Health insert ignore into journalissuearticles values(NIH);. We aimed to investigate the biochemical and insulin resistance-related markers of PCOS patients according to different diagnostic criteria. Material and methods: 1299 patients admitted to our clinic retrospectively analyzed. Following the inclusion and exclusion criteria, 200 patients with Rotterdam insert ignore into journalissuearticles values(Group 1);, 182 patients with AES insert ignore into journalissuearticles values(Group 2);, and 180 patients with NIH insert ignore into journalissuearticles values(Group 3); criteria were included in the study. Results: Waist/hip ratio among all groups insert ignore into journalissuearticles values(p1 = 0.002; p2 = 0.0001; p3 = 0.0001);, LH/FSH ratio between Group 1 and 3 insert ignore into journalissuearticles values(p2=0.017);, AST between Group 2 and 3 insert ignore into journalissuearticles values(p3 =0.012);, DHEA-S and modified Ferriman–Gallwey score between Group 1 and 2 insert ignore into journalissuearticles values(p1 = 0.041; p1 = 0.013, respectively); and Group 1 and 3 insert ignore into journalissuearticles values(p2= 0.003; p2 = 0.04, respectively); were significantly different. A significant difference was detected between Group 1 and 3 in body mass index ≥ 25 insert ignore into journalissuearticles values(kg/m2); insert ignore into journalissuearticles values(p = 0.006);. A significant difference was detected among all groups in waist circumference ≥ 88 cm insert ignore into journalissuearticles values(p1 = 0.0001, p2 = 0.0012, p3 = 0.004);. Conclusion: The rate of metabolic syndrome was found to be higher in patients diagnosed with Rotterdam criteria, the rate of insulin resistance with NIH criteria, and the rate of dyslipidemia with AES criteria. However, these differences were not statistically significant.
Keywords : Polikistik over sendromu, Metabolik sendrom, dislipidemi, Rotterdam, AES, NIH, polycystic ovary syndrome, metabolic syndrome, dyslipidemia

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