Rare occurrence of coexistent squamous cell carcinoma and basal cell carcinoma in a case of Xeroderma Pigmentosum

Authors : Suguna VENUGOPAL, Aparna MURALİDHAR, Hemalata MAHANTAPPA, Sadaf AHMAD

Pages : 90-92

Doi:10.25000/acem.720032

View : 31 | Download : 13

Publication Date : 2020-08-31

Article Type : Other Papers

Abstract :Xeroderma Pigmentosum is an inherited disorder of DNA repair characterised by defective nucleotide excision repair, which is involved in repairing ultraviolet rays induced cross linking of pyramidine residues. Affected individuals are at increased risk of development of mucocutaneous cancers at a much earlier age than normal. This genodermatosis affects both sexes and all races. The incidence in India is still unknown. We report one such case of a nine year old boy with co-existent squamous cell carcinoma and basal cell carcinoma of the face.
Keywords : Xeroderma Pigmentosum, DNA repair, Ultraviolet rays

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