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  • Journal of Basic and Clinical Health Sciences
  • Volume:5 Issue:1
  • Organoid As a Novel Technology for Disease Modeling

Organoid As a Novel Technology for Disease Modeling

Authors : Tolga SEVER, Ilgin CEVIK, Gizem ÇALIBAŞI KOÇAL, Ender Berat ELLİDOKUZ, Yasemin BAŞBINAR
Pages : 94-101
Doi:10.30621/jbachs.868837
View : 39 | Download : 11
Publication Date : 2021-02-26
Article Type : Review Paper
Abstract :The organoid technology is capable to create more real-like in vitro models in terms of structure and function of the origin of the tissue. Since the three-dimensional model is able to illustrate disease pathology, cell differentiation, and recapitulation of self-renewal, lead organoid technology as a promising disease model to fill the gap between conventional two-dimensional, and in vivo disease models. The review describes the recent development of organoid disease modeling approaches.
Keywords : Organoid, Disease modeling, Stem cell

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