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  • Journal of Basic and Clinical Health Sciences
  • Volume:5 Issue:1
  • Possible Therapeutic Role of Cholinergic Agonists on COVID-19 related inflammatory response

Possible Therapeutic Role of Cholinergic Agonists on COVID-19 related inflammatory response

Authors : Elif BARIŞ, Mualla ARICI
Pages : 102-108
Doi:10.30621/jbachs.869857
View : 44 | Download : 8
Publication Date : 2021-02-26
Article Type : Review Paper
Abstract :Severe acute respiratory syndrome-corona virus-2 insert ignore into journalissuearticles values(SARS-CoV-2); or coronavirus infectious disease insert ignore into journalissuearticles values(COVID-19); outbreak is continued to spread all over the world recently with the high mortality and morbidity rates. It is also known well coronavirus infectious disease is leading causes of acute lung injury and acute respiratory distress syndrome insert ignore into journalissuearticles values(ARDS);, septic shock and multi organ failure. Current treatment of COVID-19 includes different strategies targeting preventing viral replication or treating secondary infections and decreasing exaggerated immune response. Although antiviral, antimicrobial, immunomodulatory agents including anti-cytokines and glucocorticoids have been currently applied; there is lack of a specific treatment for COVID-19. In this review, possible therapeutic roles of cholinomimetic drugs in the control of COVID-19 are discussed.
Keywords : Cholinomimetic drugs, COVID 19, SARS CoV 2, Cytokine Storm

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