Comparison of the Effects of Clinical Outcomes on the Number of Attacks in the Course of Ulcerative Colitis: A Single Center Study

Authors : Hakan ŞIVGIN, Abdurrahman ŞAHİN, Şirin ÇETİN

Pages : 665-670

Doi:10.16899/jcm.1308661

View : 58 | Download : 76

Publication Date : 2023-07-31

Article Type : Research Paper

Abstract :Aim: The aim of this study was to find the factors affecting the frequency of attacks of patients diagnosed with ulcerative colitis insert ignore into journalissuearticles values(UC);. Method: In our single-center retrospective descriptive study, 40 UC patients who admitted to our hospital for follow-up from January 2021 to December 2022. The baseline demographic and clinical characteristics, laboratory values and, treatments during the disease course were compared among patients with number of attacks < 2 per year insert ignore into journalissuearticles values( Group1); and number of attacks ≥2 per year insert ignore into journalissuearticles values( Group 2);. Results: There were 25 insert ignore into journalissuearticles values(male∕female:11∕14); patients in Group 1 and 15 insert ignore into journalissuearticles values(male∕female:7∕8); patients in Group 2. No statistically significant difference was found between the mean age, sex, age of diagnosis, duration of disease, co-morbidities and extraintestinal involvement of both groups. The median CRP values were significantly higher in the Group 2, compared to the group 1 insert ignore into journalissuearticles values(P = 0.04);. There was statistically significant differences between groups in terms of endoscopic severe activity insert ignore into journalissuearticles values(12% vs, 40%; p<0.001);, left-sided involvementinsert ignore into journalissuearticles values(60% vs, 40%; p=0.02);, pancolonic involvement insert ignore into journalissuearticles values(8% vs, 33%; p<0.001);, the presence of blood in stool at the time of diagnosis insert ignore into journalissuearticles values(80% vs 100%; p=0.03);, use of biologic agents insert ignore into journalissuearticles values(16% vs 40%; p< 0.001); and steroids insert ignore into journalissuearticles values(16% vs 33%; p=0.02);. Conclusion: In UC patients who have ≥2 attacks per year presented with more advanced clinical features at onset and more severe outcomes than the number attacks < 2 per year. Blood in stool symptom and clinical parameters of severity index at the time of diagnosis are important criteria to be considered in determining the number of attacks in follow-up.
Keywords : Ülseratif Kolit, Atak, Klinik Parametreler

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