RELATIONSHIP BETWEEN ELECTROCARDIOGRAPHY AND ELECTROLYTES BEFORE AND AFTER DIALYSIS IN HEMODIALYSIS PATIENTS

Authors : Semahat Karahisar Şirali
Pages : 204-209
Doi:10.16899/jcm.1502013
View : 79 | Download : 25
Publication Date : 2024-07-31
Article Type : Research Paper
Abstract :Background: Cardiovascular events are the most important cause of mortality in hemodialysis patients. Rapid volume changes and electrolyte shifts during dialysis lead to arrhythmias. Objective: We aimed to determine whether there is a relationship between electrocardiographic (ECG) wave and interval changes and electrolyte levels before and after hemodialysis in dialysis patients. Materials and Method: A total of 112 patients undergoing hemodialysis three times a week for four hours for more than six months were included in the study. Before and after hemodialysis, 12-lead ECG, weight, arterial blood pressure, hemogram, biochemistry, and demographic data were recorded. Waves and intervals were calculated from the 12-lead ECG taken before and immediately after dialysis, and the relationship with serum electrolyte levels was evaluated. P<.05 was considered significant. Results: Among the patients, 51.8% were female, and the mean age was 49.83(±18.69) years. Post-dialysis RR interval correlated negatively with phosphorus (p=.007) and negatively with uric acid (p=.013). Pre-QTc correlated negatively (p=.008) moderately with uric acid and negatively (p=.016) moderately with sodium. In linear regression analysis, phosphorus (p=.007) and uric acid (p=.013) were significant on post-RR, uric acid (p=.008) was significant on pre-QTc, sodium (p=.016) and calcium (p=.027) were significant on post-QTc. Conclusion: The negative correlation between post-dialysis RR interval and phosphorus and uric acid, between pre-dialysis QTc and uric acid, and between post-dialysis QTc and sodium makes ECG interpretation and arrhythmia risk assessment difficult as a result of volume and electrolyte shifts.
Keywords : Hemodialysis, electrocardiography, electrolytes

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