Comparison of inflammation scores of patients diagnosed with hyperemesis gravidarum who applied to the emergency clinic and were hospitalized with pregnant women with a normal course.

Authors : Özlem Dülger, Hatice Şeyma Akça
Pages : 240-244
View : 78 | Download : 94
Publication Date : 2024-09-25
Article Type : Research Paper
Abstract :Aim We aimed to compare systemic inflammatory markers ((NLR (neutrophil/lymphocyte ratio), PLR (platelet/lymphocyte ratio), MLR( monocyte/lymphocyte ratio), SII (systemic immune-inflammation index) and SIRI (systemic inflammation response index)) in patients diagnosed with HEG with normal pregnant women in the first trimester. Materials and Methods The study included 52 pregnant women who applied to the emergency gynecology clinic between the 7th and 12th weeks of pregnancy and were hospitalized due to 2+ ketonuria. The control group consisted of healthy pregnant women at the same gestational age who applied to the gynecology clinic. Statistical analysis was performed with the SPSS (Statistical package for Social Sciences-SPSS Inc., version 20.0; Chicago, IL) program. Results There was no statistically significant difference between the groups in terms of maternal age, parity, body mass index (BMI) and elective curettage numbers (p>0.05). When platelet, monocyte, leukocyte and lymphocyte values were compared between the two groups, no difference was found (p>0, 05). However, when neutrophil count, NLR and PLR results were evaluated, we observed a statistically significant difference (p>0.05). We also found that combined inflammatory indices, including SII and SIRI, were significantly higher in Group HEG (p=0.000 and p=0.0011, respectively). Conclusion The results of our study showed that neutrophil and combined systemic inflammatory indices (NLR, PLR, SII, SIRI) were associated with the presence of HEG. According to our results, NLR was determined to have the strongest diagnostic efficacy in detecting the presence of HEG.
Keywords : kombine sistemik inflamatuar indeksler, hiperemezis gravidarum, gebelik

ORIGINAL ARTICLE URL