- Journal of Medicine and Palliative Care
- Volume:4 Issue:4
- The importance of serum estrone level in cases of chronic venous insufficiency in the lower extremit...
The importance of serum estrone level in cases of chronic venous insufficiency in the lower extremity
Authors : Rukiye Ada BENDER, Baran ŞİMŞEK
Pages : 302-305
Doi:10.47582/jompac.1322381
View : 62 | Download : 45
Publication Date : 2023-08-30
Article Type : Research Paper
Abstract :Aims: Chronic venous insufficiency insert ignore into journalissuearticles values(CVI); is a condition characterized by abnormal venous flow dynamics in the lower limbs and is associated with various risk factors such as pregnancy, age, obesity, and high estrogen states. One of these estrogens, estrone, is known to have cardioprotective effects. The study aimed to evaluate the relationship between estrone levels in women with CVI and healthy women. Methods: Clinical and laboratory data from 39 women with CVI and 31 healthy women without CVI were collected. All participants underwent spectral Doppler examinations and combined B-mode imaging to assess the severity of CVI. Results: The results showed a statistically significant increase in the diameter of the vena saphenous magna in the CVI group compared to the healthy control group insert ignore into journalissuearticles values(p<0.05);. However, there were no significant differences in estrone levels between the two groups. Besides, significant correlations were observed between estrone levels and age insert ignore into journalissuearticles values(r: -0.351; p=0.028);, BMI and ageinsert ignore into journalissuearticles values(r: 0.374; p=0.019);, and BMI and abdominal circumference insert ignore into journalissuearticles values(r: 0.700; p<0.001); in the CVI group. Conclusion: Our study suggests that estrone levels may have a protective effect on CVI pathogenesis. The observed effect of estrone on women with CVI may be attributed to its different receptor-level effects compared to estradiol. Further research is necessary to fully elucidate the contribution of estrone to CVI and its underlying mechanisms.Keywords : Kronik venöz yetmezlik, estron, kardiyoprotektif etki, östrojen
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