Colonoscopic evaluation of acromegalic patients: a single center experience

Authors : Yasemin Emür Günay, Serdar Durak, Arif Mansur Coşar, Murat Erkut, Sami Fidan

Pages : 395-399

Doi:10.47582/jompac.1345430

View : 86 | Download : 94

Publication Date : 2023-10-27

Article Type : Research Paper

Abstract :Aim: To investigate the importance and necessity of colonoscopic screening in patients with acromegaly. Methods: This study included 82 patients with acromegaly and, 82 healthy individuals as the control group who underwent screening colonoscopy in the Gastroenterology Department of Karadeniz Technical University, between January 2008-January 2021. Results:The mean age of the patients was 45.71 ± 12.61 years at the time of acromegaly diagnosis. 51.2% (n=42) of patients were female. Abnormal findings including evidence of polyps, and inadequate bowel preparation were significantly more common in the acromegaly group than the control(p<0,05). The GH level measured at the time of diagnosis was significantly higher in patients with acromegaly diagnosed with inadequate bowel preparation (p<0,05). There was no significant difference between the two groups in non-polyp colonoscopy findings, polyp localization, histologic types and colorectal cancer. Conclusion: It would be reasonable to perform bowel preparation in patients with acromegaly (especially those with high GH at the time of diagnosis) using an approach different from standard bowel preparation, as the rate of inadequate bowel preparation is higher in this group of patients.
Keywords : Akromegali, Kolonoskopi, Büyüme hormonu, Kolon polipleri

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