Assessment of Alterations in Cerebrospinal Fluid in Acute and Chronic Infarcts Utilizing Computed Tomography

Authors : Serkan Ünlü, Bulent Petik, Mehmet Akçiçek, Mehtap Ilgar

Pages : 79-83

Doi:10.58651/jomtu.1818474

View : 57 | Download : 87

Publication Date : 2025-12-31

Article Type : Research Paper

Abstract :Objective: This study aims to examine the differences in cerebrospinal fluid among patients with acute infarcts, chronic infarcts, and healthy controls by evaluating the density of cerebrospinal fluid via computed tomography (CT) scans of the brain. Materials and Methods: In this study, density measurements of cerebrospinal fluid (CSF) were retrospectively conducted from the lateral ventricle in a sample of 128 patients. The analysis incorporated diffusion-weighted magnetic resonance imaging (DWI) alongside CT scans of the brain. A circular region of interest (ROI) with an area of 0.25 cm² was consistently applied for the density measurements in each case. Results: The analysis of mean intraventricular density values in relation to infarct status revealed that individuals with acute infarction exhibited a mean density of 5.79 HU, which was the lowest recorded, while those without infarction had a mean density of 6.36 HU, representing the highest value. Conclusions: The analysis of changes in CSF using CT in acute and chronic stroke conditions plays a vital role in understanding the extent of neurological injury and in the development of appropriate therapeutic interventions. Evaluation of changes in CSF in acute and chronic infarctions plays a critical role in understanding the course of the disease.
Keywords : Bilgisayarlı tomografi, BOS, Yoğunluk, Enfarktüs

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