Propylthiouracil-Induced neutropenia coinciding with newly diagnosed Crohn’s disease

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Journal of Medical Topics and Updates
Cilt: 4 Sayı: 3
Propylthiouracil-Induced neutropenia coinciding with newly diagnosed Crohn’s disease

Propylthiouracil-Induced neutropenia coinciding with newly diagnosed Crohn’s disease

Authors : Hacı Mehmet Çitil, Mustafa Eray Dağdeviren, Cevat Gençer, Lezan Keskin, Bahadır Öndeş, Burhan Hakan Kanat, Gökhan Söğütlü

Pages : 113-117

Doi:10.58651/jomtu.1835987

View : 359 | Download : 348

Publication Date : 2025-12-31

Article Type : Other Papers

Abstract :Agranulocytosis is a serious side effect of antithyroid drugs (ATDs) in patients with hyperthyroidism. Diabetic ketosis is an acute complication of diabetes mellitus (DM) that can be triggered by conditions such as infection, stress, and noncompliance with treatment. Crohn’s disease (CD) is a chronic inflammatory disease of the digestive system and can present with life-threatening complications such as intestinal perforation. A 42-year-old woman with a history of DM, epilepsy, and hyperthyroidism presented with fatigue, sore throat, and joint pain. This is a rare case of Crohn’s disease diagnosed after an intestinal perforation during insulin infusion, plasmapheresis, and steroid therapy following diabetic ketoacidosis and neutropenia. This case highlights the coexistence of these three rare conditions in a single patient.
Keywords : Diyabetik ketoz, agranülositoz, nötropeni, chron hastalığı

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