Metabolik Asidozda Arteriyal, Serebro-Spinal pH ilişkisi ve NaHCO3 Tedavisinde Cevabı

Authors : S KAPICIOĞLU, A GÜRÇAY, F TANYERİ

Pages : 0-0

Doi:10.5835/jecm.v4i4.857

View : 35 | Download : 9

Publication Date : 2009-12-30

Article Type : Other Papers

Abstract :SUMMARY The relationship of arterial and cerobro-spinal fluid pH in metabolic aci¬dosis and its response to NaHCO3 therapy Blood and CSF pH ieveis are measured in 16 patients with metabolic acidosis, and 8 patients with normal acid-base balance. In normal patients CSF pH was 7.39 + 0.05, arterial pH was 7.40 ``+0.03. In metabolic acidosis these measurements were 7.32 + 0.11 and 7.22`+` 0.10 respectively. Arterial pH rose as CSF pH fell 2 and 4 hours after NaHCOa infusion and CSF pH started to rise again after 4 hours reaching a stable level in 6 hours. These results indicate that in.metabolic acidosis CSF pH is kept normal or near normal levels while arterial pH is low and NaHCOa therapy causes a depression in the CSF pH while arterial pH increases. özet Metabolik asidozlu , asit-baz dengesi normal olan hastada kan ve serebrospinal sıvı insert ignore into journalissuearticles values(CSF); pH değerleri incelendi. Normal hastalarda CSF pH = 7.39 + 0.05 arteriyal pH ise 7,40 + 0,03 idi. Metabolik asidozlu vakalarda bu değerler 7,32 ± 0,11 ve 7,22.+0,10 bulundu. NaHCQ3 infüzyonundan sonraki 2 ve 4 saatlerde arteriyal pH artarken CSF pH alçaldı. 4 saatten sonra ise CSF pH da artma oldu ve 6 saatte sabit değerlere ulaştı. Bu sonuçlar metabolik asidozda arteriyal pH`nın düşük olmasına karşılık CSF pH`nın normal veya ona yakın değerlerde korunduğunu, NaHCOj tedavisi ile arteriyal pH artarken CSF pH`nın azaldığını göstermektedir.
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