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  • Journal of Experimental and Clinical Medicine
  • Volume:15 Issue:4
  • Histopathological Findings Of Helicobacter Pylori Infectıon İn Endoscopic Antral Biopsy

Histopathological Findings Of Helicobacter Pylori Infectıon İn Endoscopic Antral Biopsy

Authors : İ AKPOLAT, E ÖZYILKAN, YS BARIŞ, L YILDIZ, F KARAGÖZ, B KANDEMİR
Pages : 0-0
Doi:10.5835/jecm.v15i4.812
View : 33 | Download : 6
Publication Date : 2009-12-23
Article Type : Other Papers
Abstract :The aims of this study are to investigate the presence of H. pylori in endoscopic antral biopsy and to evaluate the histopathological features in H. pylori positive biopsy specimens. One hundred sixty-six biopsy specimens obtained from antrum by upper gastrointestinal endoscopy were studied. Microscopic examination was normal in eight cases and H. pylori was negative in all of these biopsy specimens. The histopathological diagnosis was nonspesific gastritis in 158 cases. Helicobacter pylori was present in 109 of the 166 insert ignore into journalissuearticles values(69.7%); biopsy specimens. The scores of mononuclear cells and neutrophil polymorph infiltration and the combination of these scores insert ignore into journalissuearticles values(inflammatory score); were significantly higher in H. pylori positive cases than in H. pylori negative cases. Lymphoid aggregates were more common in H. pylori positive cases. Lamina propria edema was less severe in H. pylori positive biopsy specimens than in H. pylori negative biopsy specimens. These results indicate that H. pylori should be searched carefully if there are histopathological findings suggesting inflammation including mononuclear cells and neutrophil polymorph infiltration in antral biopsy specimens. Endoskopik antral biyopsilerde Helicobacter Pylori İnfeksiyonunda Histopatolojik Değişiklikler Bu çalışmanın amaçlan endoskopik antral biyopsilerde H. pylorinin varlığını ve H. pylori pozitif biyopsi örneklerinde histopatolojik değişiklikleri incelemektir. Üst gastrointestinal sistem endoskopisi ile alman 166 biyopsi örneği çalışılmıştır. Mikroskopik incelemede normal olan 8 vakada H. pylori negatif idi. 158 vakada ise histopatolojik tanı nonspesifik gastrit idi. 166 biyopsi örneğinin 109 tanesinde insert ignore into journalissuearticles values(%69.7); H. pylori pozitif olarak bulundu. H. pylori pozitif olan vakalarda H. pylori negatif olan vakalara kıyasla mononükleer hücre ve polmorf nötrofil infiltrasyon skoru ile bu skorların kombinasyonu insert ignore into journalissuearticles values(inflamatuvar skor); anlamlı derecede yüksekti. H. pylori poziüf vakalarda lenfoid agrégat daha sık idi. H. pylori pozitif olan vakalarda H. pylori negatif olan vakalara kıyasla lamina propria ödemi daha az şiddetli idi. Bu sonuçlar, antral biyopsi örneklerinde mononükleer hücre ve po-limorf nötrofil infiltrasyonu gibi inflamasyonu düşündüren histopatolojik bulguların varlığında H. pylori`nin dikkatle aranması gerektiğini göstermektedir.
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